(R)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl - Names and Identifiers
Name | (R)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl
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Synonyms | (R)-2,2'-Bis[bis(3,5-trifluoroMethylphenyl)phosphino]-4,4',6,6'-tetraMethoxybiphenyl (R)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl (R)-2,2'-Bis[bis(3,5-trifluoroMethylphenyl)phosphino]-4,4',6,6'-tetraMethoxybiphenyl (R)-BTFM-Garphos Phosphine, 1,1'-[(1R)-4,4',6,6'-tetramethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-bis[3,5-bis(trifluoromethyl)phenyl]-
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CAS | 1365531-84-5
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(R)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl - Physico-chemical Properties
Molecular Formula | C48H28F24O4P2
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Molar Mass | 1186.64 |
Boling Point | 722.5±60.0 °C(Predicted) |
Water Solubility | Insoluble in water. |
Appearance | crystal |
Color | white |
Storage Condition | Room Temprature |
Sensitive | Air Sensitive |
(R)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl - Introduction
(R)-2,2 '-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6 '-tetramethoxy)-1,1'-biphenyl is an organic compound commonly referred to by the abbreviation BTMOP. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C44H34F6O4P2
-Molecular weight: 838.66g/mol
-melting point: 170-172 ℃
-Boiling point: 427.2 ℃ (forecast data)
-Solubility: better solubility in common organic solvents
Use:
- (R)-2,2 '-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6 '-tetramethoxy)-1,1'-biphenyl is a chiral pharmaceutical intermediate that can be used to synthesize chiral organic compounds.
-It acts as a chiral ligand in metal-catalyzed reactions and is used to catalyze asymmetric synthesis reactions.
Preparation Method:
(R)-2,2 '-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6 '-tetramethoxy)-1,1'-biphenyl can be obtained by chemical synthesis. One commonly used synthetic route is through the reaction of a phenylboronic acid derivative with bis (3,5-trifluoromethylphenyl) phosphine iodide to form an intermediate followed by a nucleophilic substitution reaction to give the final product.
Safety Information:
Last Update:2024-04-09 02:00:49